Cech, playing his first game back at the stadium since fracturing his skull in the same fixture last season, mistimed his punch and allowed Reading substitute Andre Bikey to score with his first touch.
But Mourinho the brave replaced former Reading favourite Steve Sidwell with Mikel John Obi and right-back Paulo Ferreira with striker Claudio Pizarro at half-time.
It meant asking winger Shaun Wright-Phillips to play at right-back and Glen Johnson to play as a central defender after Ricardo Carvalho was forced out of the game...
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